General filling machine to achieve foam free aseptic filling common methods
Release Date:2022-10-20 Views:1216

The first is the creation and maintenance of the sterile environment

The first is the creation and maintenance of the sterile environment

Space sterilization: Before the filling starts, a variety of methods will be used to strictly clean and sterilize the filling area.

Air purification: Through efficient air filters, filtering tiny particles and microorganisms in the air to ensure that the air entering the irrigation area is sterile, clean, and the sterile layer flow air in the positive pressure can reach the required Cleanness


Material treatment

Material sterilization: The materials to be filled need to be sterilized in advance.

Concerned conveying: The materials after sterilization treatment through a closed pipeline or conveying system are transported to the filling unit under aseptic conditions to avoid external pollution during the conveying process, ensuring that the material still keeps sterile when entering the filling machine and still keeps sterile. state


Container preparation

Container cleaning: Before entering the irrigation area, a sterile container must go through strict cleaning procedures to remove the surface dirt, dust, and possible microorganisms.

Container sterilization: According to the material and requirements of the container, appropriate sterilization methods, such as high -temperature steam sterilization, radiation sterilization, etc., sterilize the container to ensure the sterile state of the container, provide sterile irrigation provision providing sterile irrigation provision Basic guarantee


Design and control of the filling system

Sterile irrigation head: The design of the filling head is fine, and it is closely related to the container during the filling process to avoid material leakage and contact with external air. At the same time, the filling head may adopt a special design, such as the anti -dripstick structure to ensure the accuracy and asepticity of the filling, and prevent the material from falling outside the container or introducing external air during the filling process to form air bubbles to form air bubbles.


Control process control: Under the synergies of the sterile protection system and the control system, the sterile container to be filled is reached to the specified position under the drive system, and the positioning device is fixed. The filling unit is extracted according to the preset parameters, and the container is accurately injected into the container by filling the needle or nozzle. The entire irrigation process is carried out in a sterile environment, strictly controlling parameters such as filling speed, pressure, and temperature to ensure the efficient, accurate and sterile of the filling, and avoiding air bubbles due to factors such as excessive irrigation speed or unstable pressure and other factors.


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